Alpha-lipoic acid, also known as thioctic acid, was discovered in 1951 as a molecule that assists in acyl-group transfer and as a coenzyme in the Krebs Cycle. In the 1980s, the scientific community realized that alpha-lipoic acid is also a powerful antioxidant.*

What sets ALA apart from other fatty acids is that it's an antioxidant in both fat- and water-soluble environments, and it's also an antioxidant in both its oxidized and reduced forms.* This is unlike vitamin C, for instance, which is a water-soluble antioxidant, as well as vitamin E, which is a fat-soluble antioxidant. ALA also increases intracellular glutathione and CoQ10 levels.* Its other mechanisms of action include promoting normal protein glycosylation and inhibiting the enzyme aldose reductase, which in turn inhibits conversion of glucose to sorbitol.*

Alpha-lipoic acid occurs naturally as a 50/50 mixture of R-lipoic acid (R-ALA) and S-lipoic acid (S-ALA). R-lipoic acid by itself functions as an essential cofactor for many enzymes involved in energy production.* It also has characteristics, including significant antioxidant effects, that contribute to liver, brain, nerve, and eye health.* Studies indicate that supplements containing only R-lipoic acid appear to be better absorbed than supplements containing both R-lipoic acid and S-lipoic acid, with results showing twice as much ALA appearing in the bloodstream after an oral dose of R-Lipoic acid.* Because R-Lipoic acid is the form best utilized by the body, Thorne provides R-lipoic acid bound to sodium, providing it in its most stable, absorbable form.*

Suggested use:
Take 1 capsule one to two times daily or as recommended by your health professional.

One Capsule Contains:
R-Lipoic Acid (as Sodium R-Lipoic Acid)* 100 mg.

*This product uses GeroNova Research's Bio-Enhanced® R-Lipoic Acid. Bio-Enhanced is a registered trademark of GeroNova Research, Inc.

Other Ingredients:
Hypromellose (derived from cellulose) capsule, Microcrystalline Cellulose, Magnesium Citrate, Calcium Laurate, Silicon Dioxide, Leucine.

Size:
60 capsules

ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

PREGNANCY
If pregnant, consult your health professional before using this product.

INTERACTIONS
There are no known adverse interactions or contraindications at publication date.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.